被公认为马凡氏综合征领域的世界权威. Dietz对基因蛋白原纤维蛋白缺陷的治疗药物进行了基因组定位和研究, which is linked to Marfan syndrome. 他的研究贡献使得对这种疾病的诊断具有针对性和准确性.
他曾获得50多项国家和国际奖项和荣誉, 包括国家马凡基金会颁发的安东尼·马凡奖和美国心脏协会颁发的倾听艺术奖.
Dr. Dietz是19个不同组织的特别审查员,其中包括 American Journal of Cardiology, the 儿童和青少年医学档案, and the 临床研究杂志. Over more than two decades, Dr. Dietz指导了75名博士前和博士后研究人员. 他在同行评议的期刊上发表了282篇原创论文, 25 textbook chapters, and 239 abstracts, 还就马凡氏综合征和相关遗传疾病进行了440多次讲座.
Dr. Dietz completed his B.S. 在杜克大学获得硕士学位.D. 来自纽约州立大学上州医学院. 在1992年加入约翰霍普金斯大学之前,他完成了儿科住院医师和心脏病学奖学金.
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- Winner - Harrington Prize, 美国临床研究协会和哈林顿研究所, 1/1/14
- 临床心脏病学Laennec临床医师/教育家讲座奖,2014年1月1日
- 2013年1月1日,美国医师协会入选者
- 2013年1月1日获得Pasarow心血管研究奖
- 哈兰德桑德斯上校医学遗传学终身成就奖,12年1月1日
- 12年1月1日,美国医学遗传学学会
- 12年1月1日,获得陶布曼翻译医学科学优秀奖
- Pruzansky讲座(年度临床遗传学会议)- ACMG, 11/1/1
- 2011年1月1日,美国国家科学院入选者
- Niccolo Paganini奖,SIMA international conference de S /≠ndrome de Marfan, 2010年1月1日
- 聆听艺术奖,基因联盟,2010年1月1日
- 约翰霍普金斯大学遗产奖,2009年1月1日
- George E. 2009年1月1日,美国心脏协会布朗纪念讲师奖
- 08年1月1日,国家马凡基金会,获“有心英雄”奖
- 人道主义奖,美国皮肤协会,2008年1月1日
- 2008年1月1日,国家科学院医学研究所入选者
- 2007年1月1日,国家人类基因组研究所科学顾问委员会主席
- 2007年1月1日当选为美国人类遗传学会董事会成员
- 圣华盛顿大学早产研究中心科学顾问委员会. Louis, 1/1/07
- 丽莲公主基金会教授,2007年1月1日
- Edmund R. 麦克劳斯基纪念讲座,匹兹堡大学,2007年1月1日
- 2007年1月1日,阿拉巴马大学伯明翰分校,Paulette Shirley Pritchett病理讲座
- 2007年1月1日,康奈尔大学威尔医学院Isadore Rosenfeld客座教授
- Robert M. Jeresaty Lecture, St. Francis Medical Center, 1/1/07
- 国会生物医学研究核心小组研讨会, 公共政策联合指导委员会, 1/1/07
- 怀特海研讨会第二十五届,麻省理工学院,07年1月1日
- Kathryn L. 2007年1月1日,印第安纳大学客座教授
- 《推荐十大正规网赌平台》编辑委员会,2007年1月1日
- Curt Stern奖获得者,美国人类遗传学学会,2006年1月1日
- Nahum J. 温纳纪念讲座,纽约医学院,2006年1月1日
- Thomas P. Graham Jr. 2006年1月1日,范德比尔特大学演讲
- Cazden讲座,俄勒冈健康科学大学,2006年1月1日
- Meinhard Robinow讲座,代顿儿童医院,1/1/06
- 2005年1月1日当选为美国临床研究学会理事
- 2005年1月1日,美国科学促进会入选者
- 2005年1月1日,凯斯西储大学威尔逊讲座
- 《全球十大外围足球平台》编辑部,2005年1月1日
- First Victor A. McKusick医学和遗传学教授,2004年1月1日
- 国家人类基因组研究所科学顾问委员会,2004年1月1日
- 2003年1月1日,美国临床研究学会入会会员
- 2002年1月1日,儿科研究学会入选者
- 2002年1月1日,Agarini基金会科学委员会主席
- 《推荐十大正规网赌平台》编辑委员会,2002年1月1日
- Pauline Wilson Horner讲座,凯斯西储大学,1/1/01
- 编辑委员会,儿科研究,1/1/01
- Director, William S. 斯迈洛马凡氏综合征研究中心,2001年1月1日
- 《推荐十大正规网赌平台》编辑部,1999年1月1日
- 1998年1月1日,国家马凡基金会专业顾问委员会主席
- 1997年1月1日被任命为霍华德休斯医学研究所的一员
- 埃尔斯特纪念讲座,西奈山大学医学院,1997年1月1日
- 1997年1月1日,病童医院客座教授及纪念讲座
- 1997年1月1日,马里兰大学医学院,获奖者纪念讲座
- 能源部BER 50周年庆典,美国国家科学院,1997年1月1日
- 编辑委员会,人类分子遗传学,1997年1月1日
- 克利夫兰诊所客座教授,1996年1月1日
- 1995年1月1日,美国西北大学医学院客座教授
- 安托万马凡奖,国家马凡基金会,1994年1月1日
- 儿科研究学会青年研究者奖,1993年1月1日
- Patrick John Niland纪念讲座,密歇根大学,1993年1月1日
- 国家马凡基金会专业顾问委员会,1993年1月1日
- Editorial Board, Genomics, 1/1/93
- 1992年1月1日,约翰霍普金斯医疗机构首位理查德·斯塔尔·罗斯研究学者
- Richard D. Rowe奖,儿科研究学会,1992年1月1日
- 哈里特·莱恩研究奖学金,儿科,1990年1月1日
- Pediatric Chief Resident, 1/1/88
- 1984年1月1日,纽约州立大学上州医学院最优等学生
- Alpha Omega Alpha,纽约州立大学上州医学院,1983年1月1日
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- Agarini基金会,科学委员会
- 美国心脏病学杂志,特别审稿人
- 美国人类遗传学杂志编辑委员会
- 美国人类遗传学杂志,特别审稿人
- 美国医学遗传学杂志编辑委员会
- 美国医学遗传学杂志,特别审稿人
- 美国人类遗传学学会提名委员会
- 美国人类遗传学学会代表,基因组行动联盟
- 儿童和青少年医学档案,特别审稿人
- 国家人类基因组研究所科学顾问委员会主席
- Cell, Ad hoc reviewer
- Circulation, Ad hoc reviewer
- 《推荐十大正规网赌平台》编辑部
- 临床与转化科学,编辑委员会
- 临床遗传学,特别审稿人
- 分子生物学与遗传学系,招生委员会主席
- 发展动力学,特别审稿人
- 国家基金会医学研究所(IOM)罕见病和孤儿产品加速研究与开发委员会, Member, Professional Advisory Board
- eLife, Editorial Board
- 欧洲人类遗传学杂志,特别审稿人
- Genomics, Editorial Boards
- 全球纤维化基金会,医学咨询委员会
- 人类遗传学博士前培训项目副主任
- 人类遗传学选择委员会委员
- 《全球十大外围足球平台》编辑委员会
- 人类分子遗传学,特设审稿人
- Human Mutation, Ad hoc reviewer
- 杰克逊实验室,诱导突变库顾问委员会
- 临床研究杂志,特别审稿人
- mckusick - nathan基因医学研究所,招聘委员会
- mckusick - nathan基因医学研究所,董事遴选委员会,1999年1月1日- 00年1月1日
- 医学科学家培训计划指导委员会(M.D./Ph.D.), Member
- Michael A. Sarnoff研究奖委员会成员
- 国家人类基因组研究所,理事会
- 2002年1月1日- 2005年1月1日,美国国立卫生研究院,哺乳动物遗传学研究部成员
- 国立卫生研究院心脏和血管疾病分部, 心血管疾病专业研究中心(SCOR)项目评估委员会
- 国家马凡基金会,专业顾问委员会,1997年1月1日
- 美国国立卫生研究院关节炎、肌肉骨骼和皮肤病咨询委员会(NIAMS), Chair
- 国家罕见疾病组织(NORD)科学咨询委员会成员
- Nature Genetics, Ad hoc reviewer
- Nature Medicine, Ad hoc reviewer
- 新英格兰医学杂志,特别审稿人
- 核酸研究,特别审稿人
- 儿科研究,编辑委员会
- 美国国家科学院院刊,特别审稿人
- 国家马凡基金会专业顾问委员会主任
- 研究奖委员会,大卫以色列马赫特纪念,成员
- 青年研究者日奖评审委员会委员
- RNA, Ad hoc reviewer
- Science, Ad hoc reviewer
- 科学翻译医学编委会
- 科学翻译医学,编辑
- Search and Screen Committee, 医学生理和代谢科, National Academy of Sciences, Member
- 美国人类遗传学会会长
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","provider_type":"Physician","provider_videos":[],"publication_text":"马凡氏综合征小鼠敲入模型的条件刺激”(基础科学会议), 在患者和小鼠模型中的修饰剂研究揭示了MFS和LDS的新治疗机会.(治疗干预的机制和选择), 第九届马凡氏综合征及相关疾病国际研究研讨会, The Marfan Foundation, Paris (France), September 2014.
马凡氏综合征及相关疾病的发病机制和治疗新见解. 美国心脏协会,BCVS会议(基础心血管科学),拉斯维加斯,内华达州,2014年7月
马凡氏综合征及相关疾病的发病机制和治疗新见解. Biología分子中心“Severo Ochoa”高级调查委员会Científicas马德里, Spain, October 2014.
马凡氏综合征及相关疾病的发病机制和治疗新见解. Charles R. 罗斯纪念,学生研究庆典,上州医科大学,锡拉丘兹,纽约,2014年4月.
马凡氏综合征及相关疾病的发病机制和治疗新见解. Laennec临床医生/教育家讲座, 美国心脏协会科学会议, Chicago, IL, November 2014.
马凡氏综合征及相关疾病的发病机制和治疗新见解. Stevenson讲座,西安大略大学,伦敦,安大略省,2014年11月.
Marfan & Loeys-Dietz. 第五届新英格兰马凡氏综合征年会 & Related Disorders. Ambrey Genetics, Marfan Foundation, 马凡基金会的MA分会和NH/VT网络, Manchester, NH, September 2014.
马凡氏综合征及相关疾病的发病机制和治疗新见解. 日本流通学会第78届年度科学会议,日本东京,2014年3月.
细胞外基质在稳态、自身免疫和纤维化疾病过程中的作用. Christian J. 2014 Lambertsen Honorary Lecture, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, April 2014.
细胞外基质在稳态、自身免疫和纤维化疾病过程中的作用. Robert Berliner教授,耶鲁大学,纽黑文,康涅狄格州,2014年4月.
细胞外基质在稳态、自身免疫性和纤维化疾病中的作用. 西北大学生命科学讲座,芝加哥,伊利诺伊州,2015年1月.
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其中一个目标是了解易患主动脉瘤的遗传因素, 这种疾病占工业化国家死亡人数的1- 2%. 他们最初的方法是研究马凡氏综合征(MFS), 一种由单个基因突变引起的包括主动脉瘤在内的遗传性疾病. 人们期望对原因有一个全面的了解, progression, 和MFS的调节将促进对血管壁生物学的更好理解.
目前正在研究的其他血管疾病包括血管性埃勒斯-丹洛斯综合征, 以及一种叫做洛伊斯-迪茨综合征的侵袭性动脉瘤表型. 我们已经证明,这些疾病的多系统发病机制与转化生长因子b (TGFb)之间的串扰有关。, 血管紧张素II (AngII)和丝裂原活化蛋白激酶途径. 这些途径可以在小鼠模型中仔细定位,为治疗这些疾病的人类提供强有力的科学依据.
A second major interest of the laboratory is to understand the mechanism of nonsense-mediated mRNA decay; to evaluate its basic biologic purpose; and to assess its role as a potent modulator of disease severity in a wide variety of genetic disorders.
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